10 Acute Lymphoblastic Leukemia (ALL) Symptoms Everyone Should Know

Symptom 4: Distinct Bone and Joint Pain

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Distinct Bone and Joint Pain
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Bone and joint pain might sound like something only the elderly complain about. However, in the context of ALL, such pain can affect anyone, regardless of age. Originating in the bone marrow, ALL causes an accumulation of immature white blood cells, leading to pressure and consequent pain.

But how does this pain feel? It’s not the fleeting ache one might feel after a rigorous workout. It’s persistent, often described as a dull throb or a sharp stabbing sensation, making movement arduous. Such pain can affect any bone, from the limbs to the spine, but it’s particularly noticeable in the long bones, like the legs and arms.

This discomfort can lead to decreased activity levels, especially in children. They might avoid play, sports, or even regular activities. In adults, it might manifest as stiffness, especially upon waking up or after periods of inactivity.

Accompanying the pain, there might be swelling or warmth over the affected bone or joint. Such physical signs are the body’s response to the rapid and abnormal cell growth within the marrow.(4)

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