10 Causes of Liver Cancer: Uncovering the Hidden Triggers

Introduction: A Closer Look at Liver Cancer

Liver cancer is a serious health concern that has been on the rise in recent years. As a life-threatening disease, it can have severe consequences for affected individuals and their families. This makes it essential to understand the various causes behind its development, so you can make informed decisions about your health and lifestyle choices.


In this article, we will delve deep into the top 10 causes of liver cancer, providing you with valuable information to help you stay informed and protect your health. So, without further ado, let’s jump right into our exploration of these critical factors that contribute to the development of liver cancer.

1. Chronic Hepatitis B and C Infections: The Silent Invaders

Chronic Hepatitis B and C Infections The Silent Invaders


Hepatitis B and C are viral infections that can cause long-term damage to the liver, eventually leading to the development of liver cancer. These viruses primarily spread through contact with infected blood, sexual contact, and sharing contaminated needles. When left untreated, these infections can progress to chronic hepatitis, cirrhosis, and eventually liver cancer.

The link between chronic hepatitis B and C infections and liver cancer is well-established. According to the World Health Organization, about 54% of liver cancer cases worldwide are attributable to hepatitis B, while 31% are due to hepatitis C. In many instances, people with chronic hepatitis are unaware of their infection, as symptoms may not appear until the disease has progressed to a more advanced stage.

Prevention and early detection of hepatitis B and C are crucial in reducing the risk of liver cancer. Vaccination against hepatitis B, practicing safe sex, and avoiding the sharing of needles are some effective preventive measures. For those already infected, antiviral medications can help slow down the progression of the disease, lowering the risk of liver cancer.

Hepatitis B is caused by the hepatitis B virus (HBV), and it is estimated that about 2 billion people worldwide have been infected with HBV. The virus can be transmitted from mother to child during childbirth, through sharing personal items like razors and toothbrushes, and through contaminated blood transfusions. Chronic hepatitis B significantly increases the risk of liver cancer.

Hepatitis C, caused by the hepatitis C virus (HCV), affects around 71 million people globally. Transmission routes for HCV are similar to those for HBV, but hepatitis C is more commonly spread through sharing contaminated needles among people who inject drugs. Unlike hepatitis B, there is no vaccine for hepatitis C, but recent advancements in antiviral medications have significantly improved the treatment success rate for HCV-infected individuals.

Both hepatitis B and C can cause liver inflammation, which can lead to the development of liver cirrhosis – a condition in which healthy liver tissue is replaced by scar tissue. Cirrhosis impairs the liver’s ability to perform its vital functions and significantly increases the risk of liver cancer. In fact, cirrhosis is the most common risk factor for liver cancer, and the majority of liver cancer cases are associated with cirrhosis caused by chronic hepatitis B or C infections. (1)

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