10 Early Signs of Multiple Myeloma: Recognizing Plasma Cell Myeloma

Sign 7: Shortness of Breath

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Shortness of Breath
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Shortness of breath, especially when not linked to known conditions like asthma, emerges as a troubling sign for multiple myeloma patients. At a glance, it might seem unrelated, but delve deeper, and you’ll find a link with the disease’s widespread effects.

A primary culprit for this symptom is anemia. In multiple myeloma, the increased proliferation of myeloma cells in the bone marrow leaves little room for healthy red blood cell production. These cells are paramount for oxygen transport throughout the body. With a reduced count, the body can’t meet its oxygen requirements, causing breathlessness. Anemia doesn’t just cause shortness of breath; it can also lead to feelings of fatigue and general lethargy.

The kidneys, when impacted by multiple myeloma, can also contribute to respiratory issues. As kidney function is compromised, fluid retention increases. This fluid can accumulate around the lungs, restricting their ability to expand fully. When lungs can’t expand as they should, it further exacerbates the feeling of being unable to breathe deeply or comfortably.

There’s a domino effect at play here. Reduced oxygen levels in the blood force the heart to work harder, pushing more blood in hopes of delivering the required oxygen. This increased strain can lead to palpitations and even chest pain. Over time, if left unaddressed, this can escalate to more serious heart conditions.

Breathlessness, particularly when it appears suddenly or worsens over a short period, should never be brushed off. When coupled with other symptoms like bone pain or frequent infections, it becomes even more critical to seek medical advice. Identifying and treating the underlying cause early can prevent more severe complications down the line. (7)

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