10 Essential Facts about Merkel-cell Carcinoma (MCC)

Fact 2: Risk Factors and Causes

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Risk Factors and Causes
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The medical world is rife with mysteries, and MCC is no exception. The exact origins of this aggressive skin cancer remain a subject of research. However, certain risk factors have been consistently associated with its onset. Foremost among these is prolonged exposure to the sun’s harmful ultraviolet (UV) rays.

Interestingly, the Merkel-cell polyomavirus has been identified as another significant risk factor. This virus is detected in a large number of MCC cases, suggesting a link. The body’s immune response, or the lack thereof, also plays a pivotal role. Individuals with weakened immune systems, whether due to conditions like HIV or treatments like organ transplants, are at heightened risk.

Age is another factor that can’t be ignored. Statistics indicate that individuals over 50 are particularly susceptible. This doesn’t mean younger individuals are immune, but the prevalence increases with age.

Additionally, a history of skin cancers can up the ante. People who have had bouts with other forms of skin cancer find themselves at a higher risk of developing MCC. This connection emphasizes the importance of regular skin screenings, especially for those with a medical history dotted with skin ailments. (2)

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