8. Age of Onset: When Symptoms Appear
The age of onset for Parkinson’s disease and Parkinsonism can also differ. Parkinson’s disease typically develops later in life, with most patients experiencing the onset of symptoms around the age of 60. However, early-onset Parkinson’s disease, which occurs before the age of 50, is also possible, although it is less common.
In contrast, the age of onset for Parkinsonism varies depending on the underlying cause. Some forms of secondary Parkinsonism, such as drug-induced or toxin-induced Parkinsonism, can occur at any age. Atypical Parkinsonism associated with other neurodegenerative diseases may have a more variable age of onset, with some forms, like progressive supranuclear palsy, typically developing in middle age, while others, like multiple system atrophy, may have a later onset.
Understanding the differences in age of onset between Parkinson’s disease and Parkinsonism can provide valuable information for healthcare providers in the diagnostic process and help guide treatment decisions. (8)