10. Fractures: The Fragile Fallout of Paget’s Disease
Fractures, or broken bones, represent a serious complication of Paget’s disease. The disease alters the normal bone remodeling process, leading to bones that are larger but weaker than healthy bone. This increased fragility makes the bones more susceptible to fractures, even from minor injuries that wouldn’t typically cause a break.
Fractures associated with Paget’s disease can occur in any bone affected by the condition. However, they’re particularly common in the long bones of the legs, such as the femur (thigh bone) and tibia (shin bone), and the vertebrae in the spine.
Fractures can cause severe pain and significantly impact a person’s mobility and quality of life. They can also lead to long-term complications. For example, a fracture in the spine can lead to chronic pain, nerve damage, and even permanent disability.
The increased blood supply to the affected bones, a characteristic feature of Paget’s disease, can also complicate fracture healing. This can result in prolonged recovery times and the need for more intensive rehabilitation.
Fracture prevention is a critical aspect of managing Paget’s disease. This can involve medication to slow the rate of bone turnover, as well as lifestyle modifications such as avoiding high-risk activities and maintaining good nutrition to support bone health.(10)
