7. Fatigue and Generalized Weakness: The Silent Drain of Paget’s Disease
While not as common as bone or joint pain, some individuals with Paget’s disease experience fatigue and generalized weakness. These seemingly unrelated symptoms can be a direct consequence of the disease or a result of other symptoms, such as chronic pain, that can interfere with restful sleep.
Paget’s disease’s impact on bone health can indirectly influence energy levels. The increased bone turnover and associated inflammation may cause a systemic response in the body, leading to feelings of tiredness or fatigue. Furthermore, the body’s increased metabolic demands to maintain the accelerated bone remodeling process can contribute to a sense of general weakness.
Fatigue and weakness may not be the first symptoms that come to mind when thinking about Paget’s disease, but they’re important to consider. These symptoms can significantly affect a person’s quality of life, reducing physical activity levels and impacting overall well-being. (7)
