Symptom 3: Fatigue and General Weakness
Amid the physical manifestations, a more intangible yet equally debilitating symptom is the consistent sense of fatigue and general weakness. Fatigue, in this context, isn’t just about feeling tired after a long day; it’s an all-encompassing weariness that doesn’t improve with rest. This fatigue can severely limit a person’s daily activities, from work commitments to personal endeavors.
In many instances, patients describe this fatigue as “bone-tired” or feeling like they’re “running on empty.” Even after a full night’s rest, waking up feeling refreshed becomes a rarity. And it’s not just the physical exhaustion; mental fatigue also becomes apparent. Tasks that once seemed simple, like making decisions or focusing on a project, might become insurmountable challenges.
Adding to the fatigue is a general sense of weakness, particularly in the muscles. Activities that require strength, even simple ones like lifting grocery bags or climbing stairs, can become a struggle. Over time, this can lead to decreased muscle mass and further loss of function.
Why does this happen? Cryoglobulinemia vasculitis can lead to reduced oxygen supply to tissues due to inflamed blood vessels, which might contribute to this overwhelming fatigue and weakness. Moreover, the body’s constant battle against inflammation can drain energy reserves. (3)
