10. Progressive Weakness: The Waning of Vitality
A pervasive symptom among PML patients is progressive weakness. This isn’t just about occasional tiredness; it’s a continuous reduction in physical vitality, making even the simplest tasks seem like Herculean challenges.
This progressive weakness can be traced back to the ongoing degradation of neural pathways due to PML. As these pathways get disrupted, the body’s ability to mobilize energy and maintain strength diminishes rapidly.
But this symptom extends beyond physical weakness. Many patients report a parallel emotional and mental exhaustion, making it challenging to engage in daily activities or even maintain social relationships. This compounded weakness can significantly reduce a patient’s quality of life, making early intervention and treatment paramount.(10)
