Symptom 2: Enlarged Lymph Nodes
Lymph nodes are akin to checkpoints in our body’s defense system. These small, bean-shaped structures play a crucial role in filtering harmful substances and assisting in immune responses. When these nodes become enlarged or swollen, it’s often a sign that the body is fighting off something – and in the case of BPDCN, it could be an accumulation of abnormal cells.
Enlarged lymph nodes, also known as lymphadenopathy, can manifest in areas like the neck, armpits, and groin. While swelling can sometimes be painless, it’s the persistence of these swollen nodes that rings alarm bells. A common cold or infection can also cause swollen lymph nodes, but they usually revert to their regular size once the infection clears.
But with BPDCN, it’s different. The lymph nodes might remain enlarged. Their consistency could also change, becoming firmer or harder to the touch. This transformation occurs due to the rapid growth of cancerous cells within the nodes, impeding their normal function.
Considering the pivotal role lymph nodes play in our immune responses, their impaired function could lead to other complications. It can reduce the body’s capability to fight off infections, making the individual more susceptible to illnesses. (2)
