10. Joint Pain and Stiffness: The Musculoskeletal Impact of Amyloidosis
Joint pain and stiffness can be symptoms of amyloidosis in women, particularly when amyloid deposits affect the joints and surrounding tissues. This can result in inflammation and damage to the cartilage, bones, and other structures within the joint. The affected joints may become swollen and stiff, making movement difficult and causing pain.
In some cases, the joint pain and stiffness associated with amyloidosis can be severe and disabling. This can have a significant impact on a person’s quality of life and ability to perform daily activities. The affected joints may become so stiff that it becomes difficult to move them at all, making it difficult to carry out even basic tasks.
In addition to joint pain and stiffness, amyloidosis can also cause other musculoskeletal symptoms, such as muscle weakness, numbness, and tingling in the limbs. In severe cases, it can even lead to nerve damage, causing permanent loss of function in the affected limbs.
Treatment for amyloidosis-related joint pain and stiffness typically involves reducing the amount of amyloid protein in the body. This can be done through a combination of medications, such as chemotherapy and immunoglobulin therapy, and lifestyle changes, such as maintaining a healthy diet and engaging in regular physical activity.
In some cases, surgical intervention may be necessary to remove the amyloid deposits from the joints. This can help to reduce pain and improve mobility. Physical therapy can also be helpful in improving joint function and reducing pain.
While joint pain can be attributed to many different conditions, ruling out amyloidosis is crucial for timely diagnosis and treatment. (10)
