6. Skin Changes: The Visible Effects of Amyloidosis
Skin changes, such as bruising, purpura (small purple spots), and thickening or discoloration of the skin, can be signs of amyloidosis in women. The build-up of amyloid can affect the normal functioning of the organs and tissues, leading to a wide range of symptoms.
The visible effects of amyloidosis on the skin can vary depending on the type and severity of the disease. Some common skin changes associated with amyloidosis include:
- Bruising and purpura: Bruising and purpura, or purple spots, may occur as a result of bleeding under the skin due to amyloid deposits affecting the small blood vessels.
- Thickening of the skin: In some cases, the skin may become thick and waxy, especially on the lower legs and feet.
- Nodules: Nodules, or small lumps, may develop under the skin, particularly on the elbows, hands, and fingers.
- Hyperpigmentation: Amyloidosis can cause darkening of the skin, known as hyperpigmentation.
- Bruising or discoloration around the eyes: This is a common sign of systemic amyloidosis, which affects the entire body.
- Rashes or hives: Some people with amyloidosis may develop rashes or hives on their skin.
The skin changes associated with amyloidosis can be distressing and have a significant impact on a person’s quality of life. However, it is important to remember that the skin changes are a result of underlying disease, and not a skin condition in and of themselves.
If you notice unusual skin changes, it’s essential to consult with a dermatologist or healthcare professional. While skin changes can be attributed to various causes, ruling out amyloidosis is important for timely diagnosis and treatment. (6)
