Symptom 4: Peripheral Neuropathy
Peripheral neuropathy in cryoglobulinemia isn’t just the ordinary feeling of your foot “falling asleep”. The sensations experienced are more profound and persistent. One might start to notice an unanticipated tingling in the fingertips or toes. This isn’t the transient prickling sensation that fades within minutes; it lingers, making its presence known during various daily activities.
Over time, that initial tingling might evolve into more pronounced feelings of numbness or even pain. Holding onto items becomes more challenging, not because of joint issues, but because the sensations in the fingers are muted. Walking might feel different, with the feet not sending the regular feedback to the brain. And then there’s pain – a sharp, shooting, or sometimes burning sensation that can come and go but leaves a lasting impact.
Peripheral neuropathy doesn’t just stop at sensations. As the condition progresses, it might start impacting motor functions. There can be a noticeable weakness in the muscles, especially those near the affected nerves. Tasks that require dexterity, like buttoning a shirt or picking up small items, become more difficult. Balance can also be affected, leading to an increased risk of falls and injuries.
The tingling, numbness, and pain can become particularly bothersome during periods of rest or inactivity. Nights can be interrupted by sudden jolts of pain or the uncomfortable sensation of numbness. Consequently, sleep disruptions can lead to day-time fatigue and decreased concentration, adding another layer to the challenges already faced. (4)
