3. Out on a Limb: Predominant Affection of Extremities
While erythema multiforme can manifest anywhere on the body, there’s a noted predilection for the extremities. The hands, feet, arms, and legs often bear the brunt of the condition, showcasing the most prominent symptoms.
Now, one might wonder, why the extremities? The exact reasons remain under exploration, but patterns over countless cases suggest these areas are more susceptible. It’s fascinating to consider how a condition might selectively favor certain parts of the body over others.
The focus on extremities also poses unique challenges. Given these are areas often exposed or used, the presence of rashes and lesions can hinder daily activities. Think about the discomfort of wearing shoes with lesions on the feet or the sensitivity of using hands with rashes.(3)
