10 Telltale Symptoms of Milroy’s Disease (MD) You Shouldn’t Ignore

Symptom 3: Upturned Toenails

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Upturned Toenails
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The physical manifestations of Milroy’s Disease are varied, but one of the most unique is the phenomenon of upturned toenails. At a glance, this might seem like a rather odd or insignificant symptom, especially when compared to the pronounced swelling of the extremities. However, this unusual nail growth is deeply intertwined with the core issues arising from the disease.

The roots of this symptom lie in the constant pressure exerted by the accumulated lymph fluid, especially in the feet. The excess fluid buildup, combined with skin changes, indirectly affects the growth direction of toenails. While each person’s experience might vary slightly, a consistent observation is that toenails begin to grow upwards instead of their regular, outward direction.

But what does this mean for the patient? Firstly, there’s the aesthetic aspect. Upturned toenails can make many self-conscious, especially in situations where their feet are exposed. However, more pressing than the cosmetic concerns are the functional problems this growth pattern poses. Toenails that grow upwards are more prone to trauma, catching onto socks or footwear, and potential subsequent infections.

The risk of infections is particularly concerning for MD patients. Given their already compromised lymphatic function, even minor infections can become significant challenges. Ensuring the toenails are meticulously cared for, regularly trimmed, and kept clean can mitigate some of these risks. (3)

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