10 Telltale Symptoms of Pancreatic Neuroendocrine Tumors (PanNETs, PETs, PNETs)

Symptom 4: Unexplained Weight Loss

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Unexplained Weight Loss
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Shedding a few pounds can be a cause for celebration for many. However, when this weight loss is significant, rapid, and without a discernible cause, it’s a red flag. The pancreas, with its dual roles in digestion and blood sugar regulation, is intricately tied to our body’s energy management. A tumor in this organ can disrupt these processes, leading to weight loss.

Firstly, the tumor can interfere with digestion. As previously discussed, digestive enzymes from the pancreas aid in breaking down food, allowing nutrient absorption. A tumor can hinder this, leading to malnutrition, even if one’s dietary habits remain unchanged. This can manifest as a rapid loss of both weight and muscle mass.

Secondly, there’s the aspect of energy utilization. PanNETs can sometimes interfere with insulin production or action, leading to fluctuating blood sugar levels. The body, unable to utilize glucose efficiently, might start breaking down fat stores for energy, accelerating weight loss. This is often accompanied by other symptoms, like excessive hunger, thirst, or frequent urination. (4)

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