Symptom 5: Diabetes
The sudden onset of diabetes, especially in adults without the typical risk factors, is concerning. The pancreas, as a hub of insulin production, is paramount in blood sugar regulation. PanNETs, through their growth or hormone production, can disrupt this delicate balance, leading to diabetes.
Initially, symptoms might be subtle. There might be a marked increase in thirst, leading to frequent drinking and, consequently, urination. Over time, as blood sugar levels remain elevated, other symptoms can manifest. This includes persistent fatigue, despite adequate rest, blurred vision, or recurrent infections. Some might also notice an unexplained increase in hunger, despite eating regular meals.
The link between PanNETs and diabetes is multifaceted. Firstly, the tumor can directly impede insulin production. As the tumor grows, it might damage the insulin-producing cells, leading to a decline in insulin levels. Secondly, certain PanNETs might produce hormones that counteract insulin, leading to resistance. This means that even if insulin is present, the body’s cells might not respond to it effectively, leading to elevated blood sugar levels.
Monitoring for diabetes is crucial, especially for those with a family history or other risk factors. Regular blood sugar checks, both fasting and post meals, can offer valuable insights. It’s also vital to be cognizant of any sudden changes in health or wellbeing, like those described above.(5)
