15 Crucial Facts You Must Know About Cerebrospinal Fluid Leak (CSFL)

Fact 7. CSFL and Connective Tissue Disorders: The Hidden Link

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CSFL and Connective Tissue Disorders The Hidden Link
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The seventh notable fact on our CSFL journey involves the surprising connection between CSFL and connective tissue disorders. Recent research indicates that individuals with certain types of connective tissue disorders may be more susceptible to developing CSFL.

Connective tissue disorders, such as Ehlers-Danlos Syndrome (EDS), are conditions that affect the tissues supporting the body’s organs and other structures. These disorders can weaken the dura mater—the tough outer layer that surrounds the brain and spinal cord—making it more prone to tearing and resulting in a CSFL.

EDS, in particular, has been closely associated with spontaneous CSFL. The disorder, characterized by overly flexible joints and stretchy, fragile skin, can also affect the dura, leading to a higher risk of spontaneous leaks. It’s essential for individuals diagnosed with connective tissue disorders to be aware of this association and watch for potential signs and symptoms of CSFL. (7)

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