Symptom 13. Diarrhea or Constipation: Gastrointestinal Indicators of Amyloidosis
The gastrointestinal (GI) tract, responsible for digestion and absorption of nutrients, can be affected by amyloidosis. Changes in bowel habits, such as diarrhea or constipation, can serve as important indicators of gastrointestinal involvement in amyloidosis.
Amyloid proteins can deposit in the tissues of the GI tract, including the stomach, intestines, and colon, disrupting their normal functions. This can lead to gastrointestinal symptoms that vary from person to person. Some individuals may experience chronic diarrhea, characterized by loose or watery stools that persist for an extended period. On the other hand, others may have recurring episodes of constipation, where bowel movements are infrequent or difficult.
These changes in bowel habits can be accompanied by other gastrointestinal symptoms such as abdominal pain, bloating, or a feeling of fullness after eating only a small amount of food.(13)
