15 Early Symptoms of Amyloidosis: First Signs to Watch Out For

Symptom 9. Enlarged Tongue: An Unusual Yet Significant Symptom of Amyloidosis

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Enlarged Tongue An Unusual Yet Significant Symptom of Amyloidosis
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Your tongue, a small but mighty muscle, performs a crucial role in your everyday life, aiding in speech, taste, and swallowing. Normally, it rests comfortably within your mouth, not drawing much attention. However, in cases of amyloidosis, this unassuming muscle can become an unexpected battleground. An enlarged tongue, also known as macroglossia, is an unusual yet significant symptom that can point towards the presence of amyloidosis.

When amyloid proteins accumulate in the tissues of the tongue, they can cause it to increase in size, becoming larger and bulkier than usual. This enlargement can lead to a range of issues, affecting your speech, swallowing, and even your overall oral health.

Macroglossia can manifest in different ways. Some individuals may notice difficulties with pronunciation or articulation, finding it challenging to form certain sounds due to the size and bulkiness of the tongue. Others may experience discomfort or pain when swallowing, as the enlarged tongue can obstruct the normal movement of food down the throat. In severe cases, macroglossia can even cause breathing difficulties by partially blocking the airway.(9)

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