Fact 10: Diabetes Connection

It’s fascinating how interconnected our body’s systems are. Elevated cortisol levels in Cushing’s Syndrome have a direct effect on blood sugar levels. Cortisol increases glucose production in the liver and decreases the effectiveness of insulin. This twin effect means that more sugar circulates in the blood, laying the groundwork for diabetes.
While many might assume this would only lead to Type 2 Diabetes, given it’s associated with insulin resistance, that’s not the entire story. Yes, Type 2 is a significant concern, but some patients might also develop characteristics of Type 1, where the body can’t produce enough insulin. This spectrum of diabetic symptoms further complicates treatment strategies.
Given the direct link between Cushing’s Syndrome and diabetes, rigorous blood sugar monitoring becomes vital. Not just after meals, but fasting glucose levels can provide insights into how the body is managing its sugar. It’s not just about pricking fingers, though. Hemoglobin A1c tests, which give a longer-term view of blood sugar control, can be particularly insightful.
If a patient with Cushing’s Syndrome develops diabetes, the treatment isn’t just about managing one or the other; it’s about a holistic approach. Medications might be necessary to control blood sugar levels, along with lifestyle changes. Dietary adjustments, emphasizing a balanced intake of carbohydrates, proteins, and fats, can help manage both conditions effectively. (10)