6. Genetic Factors and LGS Prognosis
One cannot discuss Lennox Gastaut Syndrome without acknowledging its potential genetic origins. In some cases, there is a clear genetic link, often inherited from an affected parent or stemming from spontaneous genetic mutations that have no prior family history.
Understanding the genetic origins is crucial, not just for treatment but also for assessing life expectancy. In some instances, the genetic mutations associated with LGS might be benign in nature, leading to a milder form of the condition. In others, the mutation might be associated with a host of other complications, thereby influencing the overall prognosis.
With advancements in genetic testing, families now have the option of gaining deeper insights into the genetic underpinnings of LGS. This knowledge can guide treatment decisions and provide clarity on potential future challenges, ultimately aiding in formulating a realistic picture of life expectancy. (6)
