13. Fanning the Flames: Factors Influencing NMOSD Relapses
In the fluctuating journey of NMOSD, periods of relapse, when symptoms worsen or new ones appear, play a central role. However, what triggers these relapses? The answer is likely multifactorial and can vary among individuals.
Infections are one common trigger. Viral or bacterial infections can stimulate the immune system, which in NMOSD, might inadvertently result in worsening neurological symptoms. The nature of these infections can range from respiratory tract infections to urinary tract infections.
Hormonal changes, particularly those related to the menstrual cycle, pregnancy, and postpartum period, might influence relapses. Studies have noted an increased risk of relapse during the first three months postpartum, although the mechanisms behind this are not well understood.
Stress, both physical and emotional, can also trigger NMOSD relapses. This highlights the importance of managing stress, promoting mental well-being, and providing comprehensive care to those living with NMOSD.
Furthermore, interruption or changes in immunosuppressive therapy used for NMOSD can lead to relapses. It underscores the importance of adhering to prescribed treatment plans.
Identifying these triggers is crucial in minimizing NMOSD relapses. By managing these factors effectively, the journey of those living with NMOSD can be made more manageable, smoothing the peaks and troughs of this condition. (13)
