15 Most Common Connective Tissue Diseases and Disorders You Shouldn’t Ignore

2. Systemic Lupus Erythematosus: The Great Imitator

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Systemic Lupus Erythematosus The Great Imitator
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Systemic lupus erythematosus (SLE), often simply referred to as lupus, is an autoimmune disorder that can affect multiple organs and systems in the body, including the skin, joints, kidneys, heart, lungs, and brain. One of the most characteristic symptoms of SLE is a butterfly-shaped rash that appears across the cheeks and bridge of the nose, also known as the malar rash. This rash is usually red or purple and can be flat or raised.

Systemic Lupus Erythematosus is an artful dodger. It’s a disease that masquerades as several other illnesses, thereby making its detection a challenge. A closer look at the symptoms can, however, peel back its disguise.

Joint pain and stiffness are common symptoms, but they tend to be less severe than in Rheumatoid Arthritis. It’s more of a discomfort than a debilitating pain, but it’s enough to raise eyebrows and warrant attention.

One unique feature of Lupus is the involvement of the kidneys. The disease can cause inflammation in the kidneys, leading to a condition known as lupus nephritis. This inflammation can lead to high protein levels in the urine and, eventually, kidney damage.

A host of other symptoms add to the complexity of Lupus. There could be neurological symptoms like seizures and psychosis. The disease can also cause chest pain due to inflammation of the lining of the heart and lungs.

Finally, Lupus doesn’t spare your blood. It can lead to anemia, leukopenia (a reduction in the number of white blood cells), or thrombocytopenia (a decrease in the number of platelets). Each of these conditions brings its set of complications, further complicating the management of Lupus. (2)

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