Akathisia: Exploring the 15 Essential Facts

Fact 3: The Difference between Akathisia and Restless Legs Syndrome

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The Difference between Akathisia and Restless Legs Syndrome
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Akathisia and Restless Legs Syndrome (RLS) are two distinct conditions that are often confused due to the presence of a similar symptom – the compelling urge to move. The distinction lies in their triggers, timing, and certain characteristic symptoms.

RLS predominantly manifests during periods of rest and inactivity, often worsening in the evening or night. It presents with an overwhelming urge to move the legs, sometimes accompanied by unpleasant sensations like crawling, creeping, or tingling. Moving the legs often provides temporary relief, distinguishing it from akathisia where relief is not always guaranteed.

Akathisia, on the other hand, is not restricted to specific times of the day and isn’t limited to the legs. The urge to move in akathisia is more pervasive and isn’t necessarily linked to periods of rest or inactivity. Further, akathisia often associates with exposure to certain medications, a correlation less common with RLS.

Separating these two conditions is critical for an accurate diagnosis and subsequent treatment. Misdiagnosis can lead to unnecessary changes in the medication regimen and the potential for exacerbating the condition. (3)

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