6. High Levels of Physical Activity: Is There a Connection?
It’s well-known that regular physical activity is a cornerstone of good health, reducing the risk of many chronic conditions. However, when it comes to ALS, the relationship with exercise seems paradoxical. Some research suggests that high levels of physical activity, especially vigorous and strenuous exercise, might be associated with an increased risk of ALS.
Athletes engaged in high-intensity sports and people with physically demanding occupations may be at a higher risk of developing ALS. This includes sports professionals, military personnel, and manual laborers. The mechanism behind this is not fully understood, but some theories propose that excessive physical activity might lead to an overproduction of free radicals, resulting in oxidative stress and potential damage to the neurons.
Contradictorily, moderate exercise appears to have a protective effect against ALS. It might support the resilience of the nervous system and motor neurons, fostering their ability to withstand stress and damage. This further highlights the complex and multifaceted relationship between physical activity and ALS.
Despite the uncertainty surrounding the role of physical activity in ALS, the evidence does not suggest that people should avoid exercise altogether. Exercise is vital for overall health, and its benefits far outweigh the risks for most people. What might be more relevant is the intensity and duration of physical activity, which calls for further exploration. (6)
