Fact 3: The Challenge of Differential Diagnosis in CAA
Distinguishing CAA from other conditions can be a real challenge. Given its silent progression and overlap with other neurological conditions, clinicians often face difficulties when attempting to diagnose CAA definitively.
CAA can often mimic the symptoms of other neurodegenerative disorders, such as Alzheimer’s disease. In fact, some individuals can have both Alzheimer’s and CAA, which further complicates diagnosis.
Even within the realm of cerebrovascular diseases, distinguishing CAA from other types of small vessel diseases isn’t easy. For instance, hypertensive arteriopathy – another condition affecting the brain’s small vessels – can present similarly to CAA.
Diagnostic uncertainty can lead to delayed treatment, making this one of the more significant challenges in managing CAA. Advanced imaging techniques and biomarkers are under investigation to aid in differentiating CAA from similar conditions.
In the light of these challenges, furthering our understanding of CAA becomes even more critical. By improving our diagnostic capabilities, we can ensure that individuals with CAA receive the appropriate care as early as possible. (3)
