Symptom 2: Tremors – The Shaking Reality of Synucleinopathy
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Second on our list of top synucleinopathy symptoms are tremors. This neurological disorder can cause involuntary shaking, often observed in the hands or legs of patients.
At the onset, these tremors may be so subtle that they are barely noticeable. They might present as a slight, rhythmic shaking of the hands when at rest, or as a quiver in the legs when standing. The tremors are often non-discriminating, affecting both sides of the body.
The tremors associated with synucleinopathy stem from the disruption of normal neuronal activity due to the accumulation of α-synuclein proteins. This disruption hampers the neurons’ ability to control muscle movements smoothly, leading to the involuntary shaking that we identify as tremors.(2)
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