Fact 13: MCI and Alzheimer’s Disease: A Possible Precursor
MCI is often considered a possible precursor to Alzheimer’s disease, one of the most common types of dementia. While not everyone with MCI will progress to Alzheimer’s, individuals with MCI are at a higher risk.
In some cases, MCI may represent an early stage of Alzheimer’s disease. This is particularly true for a subtype of MCI known as amnestic MCI, which is characterized by significant memory impairment. Studies show that individuals with amnestic MCI are more likely to develop Alzheimer’s disease compared to those with non-amnestic MCI.
Despite this connection, it’s important to remember that MCI does not always lead to dementia. Many people with MCI remain stable or even revert back to normal cognition. This variability reflects the complex nature of MCI and Alzheimer’s disease, and the myriad factors that influence their progression.
The link between MCI and Alzheimer’s disease highlights the continuum of cognitive health—from normal cognition to MCI to dementia. It underscores the importance of early detection and intervention, offering the best chance to slow cognitive decline and maintain cognitive health. (13)