Fact 8. Role of Genetics in Dementia and Life Expectancy: Decoding the Hereditary Factors
The field of genetics offers fascinating insights into many health conditions, and dementia is no exception. Genetic factors not only influence the risk of developing the disease but also shape its progression and, by extension, life expectancy. Certain genetic mutations and variations can predispose individuals to different types of dementia, each with its unique progression trajectory and impact on life expectancy.
For instance, early-onset familial Alzheimer’s disease, a rare form of dementia, is directly linked to specific genetic mutations. Individuals carrying these mutations are almost certain to develop Alzheimer’s at a relatively young age.
The disease progression in these cases can be aggressive, impacting life expectancy. This is in contrast to the more common late-onset Alzheimer’s disease, where the genetic predisposition is less clear-cut, and the disease progression varies significantly among individuals, affecting life expectancy differently. (8)
