Symptom 6: Skin Changes

One of the more visual symptoms of MEN, particularly MEN2A, is skin changes. This could include the development of bumps or lumps under the skin, known as lipomas, or the occurrence of skin lesions called angiofibromas.
Lipomas are benign fatty tumors that can occur anywhere in the body but are most common on the trunk, shoulders, and neck. While they’re typically not painful, they can cause discomfort if they press against nerves or restrict movement.
Angiofibromas, on the other hand, are small, red or pink lesions that typically occur on the face. They’re benign but can cause cosmetic concerns for some individuals. Skin changes can provide visible signs of an underlying MEN condition and should be evaluated by a healthcare professional. (6)