4. The Silent Progression of Muscle Wasting: A Physical Testament to HIBM
Muscle wasting, or muscle atrophy, is a physical manifestation of HIBM that often follows the onset of muscle weakness. This symptom reflects the gradual loss of muscle mass over time due to the disease’s progression.
Muscle wasting is visually perceptible, often noticed by individuals themselves or their family members. It usually begins in the distal muscles, such as those of the hands and feet, before progressing to affect the larger, proximal muscles. This change can result in altered physical appearance and can contribute to increasing disability as the disease progresses.
Recognizing muscle wasting as a key symptom of HIBM is critical in understanding the disease’s trajectory. While disconcerting, this symptom provides a visible testament to the ongoing changes in the body and serves as a reminder of the importance of early intervention and management. (4)
