15. A Test of Stamina: Fatigue in Friedreich’s Ataxia
Fatigue, a pervasive and oft-overlooked component of Friedreich’s Ataxia, is another facet that merits discussion. This is not just regular tiredness; it’s a profound, unrelenting exhaustion that does not necessarily improve with rest.
Those with FRDA frequently report fatigue, and it’s not hard to see why. Navigating the world with impaired coordination and strength is a monumental task. Every movement, every step, requires extra effort. The body is in a constant battle, trying to accomplish everyday activities that many take for granted.
Fatigue in FRDA might also be linked to the body’s cellular powerhouses – the mitochondria. These structures, which generate most of our body’s energy, are believed to be dysfunctional in FRDA. This could explain the chronic tiredness: it’s as if the body is trying to run a marathon on an empty tank. (15)
