3. Leading Causes and Risk Factors: The Underlying Triggers of HCC
When exploring the maze of HCC, certain pathways seem to dominate. Hepatitis B and C viral infections stand out. These viruses directly attack the liver, paving the way for chronic liver damage and setting the stage for potential carcinogenesis.
Alcohol, though enjoyed globally as a recreational beverage, has a dark side. Chronic and excessive consumption wreaks havoc on the liver, resulting in conditions like fatty liver and cirrhosis. Over time, these conditions can act as a springboard for HCC.
Another emerging concern is non-alcoholic fatty liver disease (NAFLD) and its more severe form, non-alcoholic steatohepatitis (NASH). Linked to obesity and metabolic syndromes, these conditions are alarmingly on the rise and could redefine HCC demographics in the coming decades.
Environmental toxins shouldn’t be overlooked. Aflatoxin, a toxin produced by fungi found on crops like peanuts and corn, has been linked to HCC. Consuming contaminated food is an indirect yet potent risk.
Last but not least, tobacco, the global villain of public health, has its part to play. While smoking is more directly associated with lung cancer, its role in aggravating liver conditions and escalating HCC risks is now undeniable. (3)
