Variety 7: Xanthine Stones
The Rare Occurrence of Xanthine Stones
Xanthine stones are a very rare type of kidney stone that can affect both men and women. They are composed of the compound xanthine, a byproduct of purine metabolism. Xanthine stones form due to a deficiency of the enzyme xanthine oxidase, which is responsible for breaking down xanthine into uric acid.
The deficiency of xanthine oxidase is typically caused by a rare genetic disorder called xanthinuria. As a result, individuals with a family history of xanthine stones or xanthinuria are at a higher risk of developing these stones.
Preventing xanthine stones involves managing the underlying genetic disorder. Individuals with xanthinuria should work closely with their healthcare providers to develop a personalized treatment plan. This plan may include dietary modifications, increased fluid intake, and medications to help control xanthine levels in the urine.
It’s also essential for individuals with xanthinuria to monitor their kidney function regularly. Regular check-ups and diagnostic tests can help detect xanthine stones early, allowing for prompt treatment and prevention of complications. (7)
