Problem 12: Lupus Nephritis
Lupus nephritis is an inflammation of the kidneys caused by the autoimmune disorder systemic lupus erythematosus (SLE). In people with lupus, the immune system mistakenly attacks healthy tissue, including the kidneys. This can lead to impaired kidney function and, in some cases, kidney failure.
Risk factors for lupus nephritis include a family history of lupus, being female, and certain genetic factors. The exact cause of lupus is not well understood, but it is thought to involve a combination of genetic, environmental, and hormonal factors.
Symptoms of lupus nephritis may include:
• Swelling in the legs, ankles, or feet
• Blood in the urine
• High blood pressure
• Fatigue and weakness
• Joint pain and stiffness
Treatment for lupus nephritis primarily focuses on managing the underlying lupus and reducing inflammation in the kidneys. This may involve medications such as corticosteroids, immunosuppressive drugs, and antimalarial medications. In severe cases, dialysis or a kidney transplant may be necessary. (12)
