Problem 9: Interstitial Nephritis
Interstitial Nephritis is a kidney disorder characterized by inflammation of the spaces between the kidney tubules. This inflammation can lead to impaired kidney function and, in some cases, kidney failure. Interstitial nephritis can be acute or chronic, with the acute form often developing suddenly and the chronic form developing gradually over time.
Causes of interstitial nephritis include:
• Certain medications, such as nonsteroidal anti-inflammatory drugs (NSAIDs), antibiotics, and diuretics
• Infections, including bacterial, viral, and fungal infections
• Autoimmune disorders, such as lupus or Sjögren’s syndrome
Symptoms of interstitial nephritis may include:
• Decreased urine output
• Swelling in the legs, ankles, or feet
• Fatigue and weakness
• Nausea and vomiting
• High blood pressure
Treatment for interstitial nephritis primarily focuses on addressing the underlying cause. This may involve discontinuing the use of certain medications, treating infections with antibiotics or antiviral medications, or managing autoimmune disorders with immunosuppressive medications. In severe cases, dialysis or a kidney transplant may be necessary. (9)
