Life Expectancy with Vascular Dementia (VaD): An In-Depth Exploration into Ten Revealing Facts

Fact 6: Impact of Gender on VaD Life Expectancy

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Impact of Gender on VaD Life Expectancy
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There’s a considerable body of research suggesting gender differences in the incidence and progression of VaD, which could indirectly affect life expectancy with the disease. The dynamics of gender differences in VaD are complex, influenced by a range of biological, social, and lifestyle factors.

For women, the post-menopausal phase presents an increased risk for the development of VaD. The decline in estrogen levels that occurs after menopause is thought to contribute to this increased risk. Estrogen has been found to have protective effects on blood vessels, helping to maintain their health and function. Consequently, a decline in this hormone could increase susceptibility to vascular damage and VaD.

In addition to the biological aspect, social and lifestyle factors might also influence the incidence and progression of VaD among women. These include the levels of stress, diet, physical activity, and social engagement, all of which can impact cardiovascular and cognitive health.

On the other hand, men are generally at a higher risk for cardiovascular diseases across all age groups. Given the direct correlation between cardiovascular health and VaD, this increased risk could influence the incidence and progression of VaD among men.

Hence, while women might be more vulnerable to VaD after menopause, the overall risk across the lifespan could be quite similar for both genders due to men’s higher susceptibility to cardiovascular diseases. This balance of factors could render gender less of a determinant for life expectancy in VaD than initially thought. (6)

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