Cause 2. Folate Deficiency: Don’t Overlook This Essential Nutrient
Folate, or vitamin B9, is another vital nutrient that plays a key role in red blood cell formation and DNA synthesis. Like vitamin B12, a deficiency in folate can lead to macrocytic anemia, as the body struggles to produce healthy, appropriately-sized red blood cells.
Poor diet is one of the primary reasons for folate deficiency. Foods rich in folate include leafy green vegetables, citrus fruits, beans, and fortified grains. Those who consume a diet low in these foods may be at risk for folate deficiency and the resulting macrocytic anemia.
Pregnant women have a higher need for folate due to the rapid growth and development of the fetus. A deficiency in folate during pregnancy can lead to complications such as neural tube defects and an increased risk of macrocytic anemia for both the mother and baby.
To address folate deficiency, it’s essential to consume a balanced diet rich in folate-containing foods or consider supplementation under the guidance of a healthcare provider. If lifestyle factors or medications are contributing to a deficiency, discussing these concerns with a healthcare professional can help identify appropriate steps to manage the deficiency and prevent macrocytic anemia. (2)
