Cause 3. Liver Disease: A Hidden Factor in Macrocytic Anemia
Liver disease is another potential cause of macrocytic anemia. The liver plays a vital role in the production of proteins and enzymes involved in red blood cell formation, as well as the storage and metabolism of essential nutrients, such as vitamin B12 and folate. When the liver is compromised due to disease or damage, its ability to carry out these vital functions can be severely impacted, potentially leading to macrocytic anemia.
There are numerous types of liver disease that can contribute to the development of macrocytic anemia, including hepatitis, cirrhosis, and fatty liver disease. Some of these conditions can be caused by excessive alcohol consumption, viral infections, or autoimmune disorders. To prevent liver disease-related macrocytic anemia, it’s crucial to adopt a healthy lifestyle that supports liver function, such as maintaining a balanced diet, exercising regularly, avoiding excessive alcohol consumption, and getting vaccinated against hepatitis, if applicable.
In cases where liver disease has already led to macrocytic anemia, treatment may involve addressing the underlying cause of the liver disease and implementing lifestyle changes to support liver health. In some cases, specific medications or even liver transplantation may be recommended to manage liver disease and its associated complications, including macrocytic anemia. (3)
