7. Anemia and Other Blood Abnormalities: The Silent Saboteurs
For many with CVID, anemia and other blood abnormalities are par for the course, but their impact is far from trivial. A low red blood cell count (anemia), low platelet count (thrombocytopenia), or low white blood cell count (neutropenia) can all emerge in the context of CVID. These abnormalities can leave patients feeling weak, increase their risk of infections, and complicate wound healing.
The roots of these hematologic issues in CVID are diverse. They may result from the body’s own immune system mistakenly targeting blood cells, a condition known as autoimmune cytopenia. Alternatively, they may stem from malnutrition due to chronic gastrointestinal issues or as a side effect of some of the medications used to manage CVID symptoms.
Addressing these blood abnormalities often requires collaboration between immunologists and hematologists. Treatment might involve medications to suppress the immune system, therapies to boost blood cell production, or in severe cases, infusions of blood products or a bone marrow transplant.
For those living with these conditions, regular blood monitoring is essential. It allows for early intervention, which can prevent complications and help maintain stability. Patient education on recognizing signs of severe anemia, infection, or bleeding is also a vital component of care. (7)
