3. Renal Complications: Unseen Damage within the Kidneys
Multiple myeloma often casts a shadow on the kidneys, leading to renal complications that might go unnoticed initially. The kidneys, those bean-shaped organs, have a monumental task of filtering out waste from our blood. But when myeloma proteins enter the picture, they can clog these renal filters.
These proteins, though minute, have a tremendous impact. Over time, they accumulate and damage the kidneys, reducing their filtering capacity. Consequently, harmful toxins that are typically excreted start building up in the bloodstream. The kidneys, in their attempt to cope, might increase urine production, leading to frequent trips to the restroom, especially at night.
Water balance in the body goes awry. Patients might notice swelling in their legs, ankles, or around the eyes. This swelling isn’t just a cosmetic concern; it’s an indication of fluid retention due to compromised kidney function. While the external swelling is visible, internally, the accumulation might lead to high blood pressure – a silent threat in itself.
Another fascinating detail about this renal-kidney relationship is the role of calcium. As myeloma affects the bones, calcium from the bones can leak into the bloodstream. Elevated calcium levels can be detrimental to kidney function, adding another layer to the already intricate complication. (3)
