Fact 15: Long-Term Prognosis and Prevention
With prompt recognition and appropriate treatment, the prognosis for Neuroleptic Malignant Syndrome (NMS) can be good. Many patients can fully recover with no lasting effects. However, the syndrome can be fatal if not recognized and treated in a timely manner. Additionally, even with treatment, a small proportion of patients may experience lasting effects or complications.
Prevention forms a key component of managing NMS. For patients who have experienced an episode of NMS, avoiding re-exposure to the offending antipsychotic drug is crucial. If antipsychotic therapy is unavoidable, it should be initiated with a different drug, starting at a low dose and gradually increasing under careful monitoring.
Patient education and awareness are also key in preventing NMS. Patients who have experienced NMS should be aware of the symptoms of the syndrome and the need to seek immediate medical help if these symptoms reappear.
Regular monitoring of patients on antipsychotic therapy can also help in the early detection and prevention of NMS. This involves monitoring for the emergence of NMS symptoms and adjusting the treatment plan as necessary. (15)
