Neuromyelitis Optica Spectrum Disorders: A Deep Dive into the Top Ten Symptoms

Symptom 5: Uncontrollable Vomiting and Hiccups – An Unexpected Manifestation

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Uncontrollable Vomiting and Hiccups - An Unexpected Manifestation
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Uncontrollable vomiting and hiccups are two symptoms of NMOSD that may initially seem out of place. However, a look at the mechanics of NMOSD shows that these symptoms can occur when the disorder affects a specific area of the brain known as the area postrema.

The area postrema serves as the vomiting center of the brain and, when inflamed, can lead to episodes of uncontrollable vomiting and hiccups. Unlike typical instances of vomiting and hiccups that have a clear cause, such as food poisoning or indigestion, these episodes are unprompted and can persist for extended periods.

These symptoms are not to be taken lightly, as persistent vomiting can lead to severe dehydration and nutritional deficiencies. The hiccups, while not dangerous in themselves, can cause considerable distress and impact an individual’s ability to eat, drink, or even sleep.

Addressing these symptoms usually involves managing the inflammation in the brain. Additionally, symptom control measures are taken to prevent dehydration and ensure the individual’s nutritional status is maintained. As with other NMOSD symptoms, the focus is on enhancing the individual’s comfort and quality of life. (5)

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