15. The Global Perspective: PBC Around the World
Primary Biliary Cholangitis does not recognize borders; it is a global issue, with cases reported from all corners of the planet. However, the prevalence and presentation of PBC can vary widely between regions. Understanding these global patterns is essential for developing international strategies for awareness, diagnosis, and management.
In Western countries, PBC is more frequently diagnosed, possibly due to better healthcare access and greater awareness among physicians. In contrast, in some developing nations, the lack of resources and medical knowledge can lead to underdiagnosis or misdiagnosis. Global collaborative efforts are therefore essential to bridge these gaps and ensure that patients worldwide receive accurate diagnoses and effective treatment.
The variation in PBC prevalence across different populations also offers insights into the interplay between genetic and environmental factors. Such epidemiological studies can lead to targeted public health interventions and inform research priorities.
Moreover, international patient registries and databases contribute to a more comprehensive understanding of PBC, facilitating research into its natural history and the effectiveness of various treatment approaches across diverse patient populations.
PBC is a disease that transcends geographical boundaries, and as such, it demands a unified global response. Sharing knowledge and resources internationally can accelerate progress in combating PBC, ultimately benefiting patients no matter where they live. (15)
