Symptom 12: Loss of Muscle Mass: When the Body Starts Wasting Away
Liver damage can contribute to the loss of muscle mass, a condition known as muscle wasting or muscle atrophy. This progressive loss of muscle tissue can have significant implications for an individual’s strength, mobility, and overall health.
The exact mechanisms behind muscle wasting in liver damage are not fully understood, but several factors contribute to this condition. One key factor is the imbalance of protein metabolism caused by liver dysfunction. The liver plays a crucial role in protein synthesis and breakdown, and when it is compromised, the normal balance is disrupted.
Additionally, the systemic inflammation associated with liver damage can accelerate muscle breakdown and impair muscle regeneration. Poor appetite, malnutrition, and reduced physical activity due to fatigue or other symptoms can also contribute to muscle wasting.
As muscle mass decreases, individuals may experience weakness, reduced physical endurance, and diminished functional ability. Tasks that were once easy to perform may become challenging, leading to a decline in overall quality of life.(12)