Symptom 13: Sensitivity to Medications: When the Usual Dose Becomes Too Much
Liver damage can impact the way the body processes medications, leading to increased sensitivity to certain drugs. What was once a standard dose may now become too much for the liver-damaged individual, resulting in adverse reactions or heightened side effects.
The liver plays a crucial role in metabolizing medications by breaking them down into inactive substances that can be safely eliminated from the body. When the liver is compromised, its ability to perform this function efficiently may be impaired. As a result, medications can accumulate in the body, leading to higher drug concentrations and an increased risk of toxicity.
Individuals with liver damage may experience heightened sensitivity to medications due to various factors. These can include reduced liver enzyme activity, decreased drug metabolism, altered drug distribution, or impaired excretion. As a result, medications that are typically well-tolerated by individuals with a healthy liver may cause unexpected reactions or require dosage adjustments in individuals with liver dysfunction.(13)