Cause 10. Chronic Inflammatory Conditions: A Prolonged Battle with Anemia
Chronic inflammatory conditions, such as inflammatory bowel disease (IBD), rheumatoid arthritis, and chronic infections, can contribute to the development of anemia. Inflammation can affect the production, lifespan, and function of red blood cells. This leads to a type of anemia known as anemia of chronic disease (ACD) or anemia of inflammation.
ACD is characterized by a disruption in iron metabolism. This leads to reduced iron availability for red blood cell production. The body may have adequate iron stores, but the iron is sequestered in storage sites and not readily available for use. Inflammation can also suppress the production of erythropoietin (EPO). It is a hormone that stimulates red blood cell production, further contributing to anemia.
Treatment for anemia caused by chronic inflammatory conditions typically involves addressing the underlying cause of the inflammation. This may include medications to reduce inflammation, such as corticosteroids, nonsteroidal anti-inflammatory drugs (NSAIDs), or biologic therapies, depending on the specific condition. In some cases, iron supplementation, erythropoiesis-stimulating agents (ESAs), or blood transfusions may be used to help manage anemia symptoms. It is essential to work closely with healthcare providers to develop a comprehensive treatment plan. (10)
