Sjögren’s Syndrome 101: 15 Key Takeaways and Facts

9. The Enigma of Sjögren’s and Joint Pain: An Unexpected Partnership

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The Enigma of Sjögren's and Joint Pain An Unexpected Partnership
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A perplexing facet of Sjögren’s syndrome is its ability to affect the joints. At first glance, a connection between a syndrome primarily known for causing dryness and joint discomfort might seem far-fetched. Yet, delve deeper, and the relationship becomes clear.

The immune system’s attack in Sjögren’s is not limited to moisture-producing glands. For some, this autoimmune response extends to the synovium – the tissue lining the joints. Inflammation here translates to pain, swelling, and, over time, potential joint damage.

But not all joint pain in Sjögren’s patients is directly due to the syndrome. Secondary complications, such as rheumatoid arthritis, can co-exist, complicating diagnosis and treatment. Teasing out the true cause is both an art and a science, requiring keen clinical acumen.(9)

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