9. High Blood Pressure – An Understated Sign of Cowden Syndrome
High blood pressure, also known as hypertension, is another symptom that has been linked to Cowden Syndrome, although it’s often overlooked. Hypertension occurs when the force of blood against the artery walls is consistently too high, leading to potential damage to the heart and blood vessels.
The connection between Cowden Syndrome and hypertension is not direct but is associated with the overall increase in abnormal cell growth due to PTEN gene mutations. Excessive cell proliferation can lead to changes in the blood vessels and the heart, thereby affecting blood pressure regulation. For instance, growths or tumors in the adrenal glands (organs that produce hormones regulating blood pressure) could lead to elevated blood pressure.
It’s essential to maintain regular blood pressure checks, particularly for individuals diagnosed with Cowden Syndrome. Given the silent nature of hypertension – often termed the ‘silent killer’ due to its lack of noticeable symptoms – regular monitoring is crucial to prevent potential complications such as heart disease and stroke.
The management of hypertension in Cowden Syndrome primarily involves lifestyle modifications and medications. Adopting a healthy diet, maintaining a regular exercise regimen, limiting alcohol, and quitting smoking can help regulate blood pressure. In some cases, antihypertensive medications may be necessary, under the guidance of a healthcare provider. (9)
